陈苏宁  

个人简介：1973年生于江苏省南通市，2003年7月获苏州大学血液病博士学位，学位论文荣获2005年全国优秀博士学位论文提名。2003年8月起于苏州大学附属第一医院血液科从事血液病临床诊疗工作。2007年4月，获得国际著名的德国洪堡基金会资助，作为洪堡学者于德国DSMZ从事白血病合作研究。担任苏州大学附属第一医院教授、主任医师、博士生导师，血液科副主任、血液研究室主任，江苏省杰出青年基金获得者、江苏省333工程重点人才（第2层次）、江苏省医学重点人才、姑苏卫生重点人才、江苏省六大高峰重点人才，江苏省特聘教授。2022年获国际专业奖项“法国圣安东尼-EBMT青年领袖奖”，2021年入选科技部中青年科技创新领军人才，2019年获评国家百千万人才工程“有突出贡献中青年专家” 中华人民共和国人力资源和社会保障部。

擅长疾病：血液肿瘤

科研情况：主要从事急慢性白血病的分子分层和精准诊断，以及分子机制研究和靶向治疗研究，目前任国家血液病临床医学研究中心副主任，江苏省血液研究所副所长，苏州大学附属第一医院血液研究室主任；入选科技部中青年科技创新领军人才、国家百千万人才、有突出贡献中青年专家、江苏省杰出青年、江苏省特聘教授、江苏省“333高层次人才培养工程”二层次。江苏省医学会第十届血液学分会委员会主任委员，中国病理生理学会第九届实验血液学专业委员会血液科副会长，中华医学会血液学分会第十一届委员会白血病-淋巴瘤学组副组长。以第一或通讯作者在Blood、Leukemia、AJH等血液学领域专业期刊发表SCI论文97篇，其中IF>10共21篇，总引用3573次，单篇最高引用121 次。2019年来，陈苏宁撰写中华医学会专家指南共识5篇；其中系统性肥大细胞增多症（SM）指南为中国首部，推动SM纳入罕见病目录，中国专家指南共识（英文版）1篇；参与讨论11篇。在国内首次获得美国白血病淋巴瘤协会科研项目资助，主持863子项目、973子课题、精准医学重大专项子课题、国家自然科学基金面上项目、江苏省杰出青年基金等科研项目10余项。获国家科技进步奖二等奖（2016，排名第3）1项、江苏省科技进步奖一等奖（2009和2015，排名第3）2项、教育部科技进步奖一等奖（2015，排名第3）1项、中华医学科技奖二等奖（2015，排名第2）1项，获2017年第十届吴孟超医学青年基金奖。

学术任职：

现任国家血液系统疾病临床医学研究中心副主任、江苏省血液研究所副所长、苏州大学附属第一医院血液研究室主任；农工党苏州市委副主委、苏州大学委员会主委；中华医学会血液学分会十一届委员兼秘书长；江苏省医学会第十届血液学分会委员会主任委员；江苏省医师协会血液科医师分会第三届委员会副会长。

教育背景（从大学本科开始，按时间倒序排序）：

(1) 2000.9–2003.6, 苏州大学, 医学部第一临床学院， 研究生，医学博士
(2) 1997.9–2000.6, 东南大学, 医学院, 研究生，医学硕士
(3) 1992.9–1997.6, 南京铁道医学院, 临床医学系, 本科，医学学士

科研与学术工作经历：

(1) 2014.10-至今, 苏州大学附属第一医院, 血液科, 教授、主任医师
(2) 2012.10-2014.9, 苏州大学附属第一医院, 血液科, 教授、副主任医师
(3) 2009.10-2012.9, 苏州大学附属第一医院, 血液科, 副主任医师、副教授
(4) 2005.10-2009.9, 苏州大学附属第一医院, 血液科, 主治医师
(5) 2003.8-2005.9, 苏州大学附属第一医院, 血液科, 住院医师

研究领域：血液肿瘤的分子机制与靶向治疗

取得研究成果和获得学术奖励情况：

1、期刊论文（近5年内发表的5篇代表性论著）
1)Xie J(#), Bao X(#), Xue SL(#), Shen H, Cen J, Yao L, Pan J, Zhu M, Liu D, Hu X, Wu Q, Zhang J, Dai H, Cao Y, He X, Tang X, Sun AN, Wang Y, Fu J, Qiu H, Yang X(*), Chen S(*), Wu D(*). Venetoclax with Decitabine as Frontline Treatment for Younger Adults with Newly Diagnosed ELN Adverse-Risk AML. Blood. 2023 Jul 21.
2)Zhu H(#), Qin Y(#), Zhang ZL(#), Liu YJ(#), Wen L(#), You MJ, Zhang C, Such E, Luo H, Yuan H, Zhou HS, Liu H, Xu R, Li J, Li JH, Hao JP, Jin J, Yu L, Zhang JY, Liu LP, Zhang LP, Huang RB, Shen S, Gao SJ, Wang W, Yan X, Zhang X, Du X, Chu X, Yu Y, Wang Y, Mi YC, Lu Y, Cai Z, Su Z, Taussig DCC, MacMahon S, Ball ED, Wang HY, Welch JS, Yin CC, Borthakur G, Sanz MAA, Kantarjian HM, Huang J(*), Hu J(*), Chen S(*). A global study for acute myeloid leukemia with RARG rearrangement. Blood Adv. 2023 Feb.
3)Liu T(#), Wen L(#), Yuan H(#), Wang Y, Yao L, Xu Y, Cen J, Ruan C, Wu D(*), Chen S(*)，Identification of novel recurrent CPSF6-RARG fusions in acute myeloid leukemia resembling acute promyelocytic leukemia. Blood. 2018 Apr;131(16):1870-1873.
4)Yao L(#), Wen L(#), Wang N(#), Liu T, Xu Y, Ruan C, Wu D(*), Chen S(*)，Identification of novel recurrent STAT3-RARA fusions in acute promyelocytic leukemia lacking t(15;17)(q22;q12)/PML-RARA. Blood. 2018 Feb;131(8):935-939.
5)Ping N(#), Sun A(#), Song Y(#), Wang Q(#), Yin J, Cheng W, Xu Y, Wen L, Yao Hong, Ma L, Qiu H, Ruan C, Wu D(*), Chen S(*), Exome sequencing identifies highly recurrent somatic GATA2 and CEBPA mutations in acute erythroid leukemia. Leukemia. 2017 Jan;31(1):195-202
6)Zhang T(#), Xu Y(#), Pan J, Li H, Wang Q, Wen L, Wu D, Sun A(*), Chen S(*). High frequency of RUNX1 mutation in myelodysplastic syndrome patients with whole-arm translocation of der(1;7)(q10;p10). Leukemia. 2017 Oct;31(10):2257-2260.
7)Wen L(#), Xu Y(#), Yao L(#), Wang N, Wang Q, Liu T, Pan J, Cen J, Zhou H, Miao M, Shao YW, Wang X, Wang X, Ruan C, Wu D(*), Chen S(*). Clinical and molecular features of acute promyelocytic leukemia with variant retinoid acid receptor fusions. Haematologica. 2018 Sep 20.
8)Ping N(#), Qiu H(#), Wang Q(#), Dai H, Ruan C, Ehrentraut S, Drexler HG, MacLeod RA, Chen S(*). Establishment and genetic characterization of a novel mixed-phenotype acute leukemia cell line with EP300-ZNF384 fusion. J Hematol Oncol. 2015 Aug 21;8:100
9)Huo L(#), Zhang Z(#), Zhou H(#), Xie J, Jiang A, Wang Q, Ding Z, Dai H, Liu D, Wu N, Qiu Q, Ma L, Wang M, Wang W, Xue S, Chen Z, Wu D, Yao H(*), Chen S(*), Shen H(*). Causative germline variant p.Y259C of DDX41 recurrently identified in acute lymphoblastic leukaemia. Br J Haematol. 2023 May 5.
10)Yao H(#), Huo L(#), Ping N(#), Liu H, Li H, Ding Z, Shen H, Xie J, Qiu Q, Ma L, Jiang A, Wang Q, Wu D, Yang X(*), Song Y(*), Chen S(*). Recurrent mutations in multiple components of the SWI/SNF complex in myelodysplastic syndromes and acute myeloid leukaemia. Br J Haematol. 2022 Jan;196(2):441-444.
11)Yao H, Pan J, Wu C, Shen H, Xie J, Wang Q, Wen L, Wang Q, Ma L, Wu L, Ping N, Zhao Y, Sun A, Chen S(*). Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22). Mol Cancer. 2015 Apr 11;14:81.
12)Xu Y(#), Sun Y(#), Shen H, Ding L, Yang Z, Qiu H, Sun A, Chen S(*), Wu (*)D. Allogeneic hematopoietic stem cell transplantation could improve survival of cytogenetically normal adult acute myeloid leukemia patients with DNMT3A mutations. Am J Hematol. 2015 Nov;90(11):992-7.
13)Wang Q(#), Cai WZ(#), Wang QR(#), Zhu MQ, Yan LZ, Yu Y, Bao XB, Shen HJ, Yao H, Xie JD, Zhang TT, Zhang L, Xu XY, Shan Z, Liu H, Cen JN, Liu DD, Pan JL, Lu DR, Chen J, Xu Y, Zhang R, Wang Y, Xue SL, Miao M, Han Y, Tang XW, Qiu HY, Sun AN, Huang JY, Dai HP(*),, Wu DP(*),, Chen SN(*),. Integrative genomic and transcriptomic profiling reveals distinct molecular subsets in adult mixed phenotype acute leukemia. Am J Hematol. 2023 Jan;98(1):66-78.
14)Chen S, Zhao W, Li J, Wu D; Lymphoid Disease Group, Chinese Society of Hematology, Chinese Medical Association. Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition). Front Med. 2022 Oct;16(5):815-826.
15)Xu X(#), Lu Q(#), Wang Z,(#) Cai P, Zeng Z, Zhang L, Wang M, Ma L, Ruan C, Chen S(*). Identification of a Novel CSNK2A1-PDGFRB Fusion Gene in a Patient with Myeloid Neoplasm with Eosinophilia. Cancer Res Treat. 2021 Jul;53(3):889-892.
16)Wang Z(#), Wen L(#), Zhang L(#), Xu X, Chen X, Yao L, Wang M, Shen Z, Mo G, Wang Y, Zhao D, Cai W, Shen J, Chi X, Xu Y, Zeng Z, Pan J, Ruan C, Wu D, Jia Z(*), Chen S(*). Identification of a novel TNRC18-RARA fusion in acute promyelocytic leukemia lacking t(15;17)(q24;q12)/PML-RARA. Mol Carcinog. 2021 Feb;60(2).
17)Xu X(#), Zeng Z(#), Huo L(#), Liu H, Yu Y, Zhang L, Cen J, Qiu H, Tang X, Fu C, Han Y, Miao M, Jin Z, Ruan C, Wu D, Chen S, Wang Q(*), Yan L(*). High expression of myocyte enhancer factor 2C predicts poor prognosis for adult acute myeloid leukaemia with normal karyotype. Br J Haematol. 2020 Apr;189(1):e23-e27.
18)Wang T(#), Wang Z(#), Zhang L, Wen L, Cai W, Yang X, Pan J, Ruan C, Wu D, Sun A(*), Chen S(*). Identification of a novel TFG-FGFR1 fusion gene in an acute myeloid leukaemia patient with t(3;8)(q12;p11). Br J Haematol. 2020 Jan;188(1):177-181.
19)Yu Y(#), Zhang T(#), Zeng Z, Wang Q, Hong Y, Shen H, Wu D, Pan J, Chen S(*), Sun A. A(*) special type of chromosome 1 abnormality in myelodysplastic syndrome patients: duplication 1q. Br J Haematol. 2020 Jun;189(5):e218-e221.
20)Tianhui Liu(#) ; Lijun Wen(#) ; Hongjian Yuan (#); Yi Wang (#) ; Li Yao; Yang Xu; Jiannong Cen; Changgeng Ruan; Depei Wu; Suning Chen(*) ,Identification ofnovel recurrent CPSF6-RARG fusions in acute myeloid leukemia resembling acute promyelocytic leukemia, Blood, 2018.2.27, online(online)
2、期刊论文（近5年内发表的其他论著）
(1) Zong, Xiangping(#) ; Yao, Hong; Wen, Lijun; Ma, Liang; Wang, Qinrong;Yang, Zhiluo; Zhang, Tongtong; Chen, Suning(*) ; Wu Depei(*),ASXL1 mutations are frequent in de novo AML with trisomy 8 and confer an unfavorable prognosis; Leukemia and Lymphoma, 2017, 58(1): 204~206
(2) Yao, Li (#); Cen, Jiannong; Pan, Jinlan; Liu, Dandan; Wang, Yong; Chen,Zixing; Ruan, Changgeng(*);Chen, Suning(*),TAF15-ZNF384 fusion gene in childhood mixed phenotype acute leukemia , CANCER GENETICS, 2017.2, 211: 1~4
(3) Yu, Yan (#) ; Zhang, Tongtong(#) ; Wang, Qinrong; Wu, Depei; Pan, Jinlan;Liang, Jianying; Chen, Suning (*); Sun, Aining (*),Counting bone marrow blasts as a percentage of nonerythroid cells improves the prognostic evaluation of MDS with erythroid predominance ;AMERICAN JOURNAL OF HEMATOLOGY, 2017.4, 92(4):E55~E57
(4) Cai, W-Z(#) ; Cen, J-N; Chen, J.; Chen, F.; Fu, C-C; Han, Y.; Jin, Z-M;Ma, X.; Miao, M.; Qiu, H-Y; Tang, X-W; Xue, S-L; Sun, A-N; Chen, S-N(*) ; Wu,D-P (*),Major molecular response prior to allogeneic hematopoietic stem cell transplantation predicts better outcome in adult Philadelphia-positive acute lymphoblastic leukemia in first remission;BONE MARROW TRANSPLANTATION, 2017.3, 52(3): 470~472
(5) Suning Chen(#) ; Stefan Nagel; Bjoern Schneider; Haiping Dai; Robert Geffers; Maren Kaufmann; Corinna Meyer; Claudia Pommerenke; Kenneth S. Thress;Jiao Li; Hilmar Quentmeier; Hans G. Drexler (*) ; Roderick A. F. MacLeod ,(*) A new ETV6-NTRK3 cell line model reveals MALAT1 as a novel therapeutic target – a short report, International Society for Cellular Oncology, 2017.10.06, 41:93~101
(6) Liangjing Xu(#); Jinge Xu(#) ; Shoubao Ma (#) ; Xiaoli Li; Mingqing Zhu;Suning Chen; Yue Han; Xiaowen Tang; Zhengzheng Fu; Huiying Qiu; Jianhua Yu(*) ; Depei Wu(*) ; Xiaojin Wu (*) ,High Tim-3 expression on AML blasts could enhance chemotherapy sensitivity, Oncotarget, 2017.6.14, 8(60): 102088~102096
(7) Guangying Sheng(#) ; Jian Zhang(#); Zhao Zeng ; Jinlan Pan; Qinrong Wang;Lijun Wen; Yang Xu; Depei Wu(*) ; Suning Chen(*)；Identification of a novel CSF3R-SPTAN1 fusion gene in an atypical chronic myeloid leukemia patient with t(1;9)(p34;q34) by RNA-Seq, Cancer Genetics, 2017.5.19, (216-217): 16~19
(8) Shuangfeng Zhang (#); Liang Ma(#) ; Yafeng Chen; Huan Xu; Suning Chen(*)；WenzhongWu(*)；Overexpression of HHEX in Acute Myeloid Leukemia with t(8;21)(q22;q22) Translocation, Annals of Clinical & Laboratory Science, 2017,47(6): 687~697
(9) Guangying Sheng(#) ; Zhao Zeng (#); Jinlan Pan; Linbing Kou; Qinrong Wang;Hong Yao; Lijun Wen; Liang Ma; Depei Wu; Huiying Qiu; Suning Chen(*),Multiple MYO18A-PDGFRB fusion transcripts in a myeloproliferative neoplasm patient with t(5;17)(q32;q11), Molecular Cytogenetics, 2017.2.27, 10
(10) Han, Qiaoyan ; He, Xuefeng; Wu, Lili; Gao, Feng; Ye, Jinsong; Wu,(#)Lingyu; Chen, Lu; Jiang, Xin; Sun, Miao (*); Chen, Suning(*),Downregulated stromal antigen 2 expression in de novo acute myeloid leukemia patients; Experimental and Therapeutic Medicine, 2017.2, 13(2): 530~534
(11) Jun Liu(#) ; Bo Guo; Zhuo Chen; Nayi Wang; Michelina Iacovino; Jijun Cheng; Christine Roden; Wen Pan; Sajid Khan; Suning Chen; Michael Kyba; Rong Fan; Shangqin Guo; Jun Lu(*) , miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism, Blood, 2017, 129(11): 1491~1502
(12) Guangying Sheng(#) ; Chaohui Dong; Ri Zhang; Miao Miao; Wu Depei; Suning Chen；Seng Chuen Tan; Chao Liu; Tengbin Xiong(*) ,Societal implications of medical insurance coverage for imatinib as first-line treatment of chronic myeloid leukemia in China: a cost effectiveness analysis, Journal of Medical Economics, 2017.4, 20(4): 371~381
(13) Maoxiang Qian(#) ; Hui Zhang(#) ; Shirley Kow-Yin Kham; Shuguang Liu;Chuang Jiang; Xujie Zhao; Yi Lu; Charnise Goodings; Ting-Nien Lin; Ranran Zhang; Takaya Moriyama; Zhaohong Yin; Zhenhua Li; Thuan Chong Quah; Hany Ariffin; Ah Moy Tan; Shuhong Shen; Deepa Bhojwani; Shaoyan Hu; Suning Chen;Huyong Zheng; Ching-Hon Pui; Allen Eng-Juh Yeoh (*); Jun J Yang(*) , Whole Transcriptome Sequencing Identified a Distinct Subtype of Acute Lymphoblastic Leukemia with Predominant Genomic Abnormalities of EP300 and CREBBP, Genome Research, 2017.2, 27(2): 185~195
(14) Chen, Meiyu(#) ; Xiong, Fei; Ma, Liang; Yao, Hong; Wang, Qinrong; Wen,Lijun; Wang, Qian; Gu, Ning; Chen, Suning (*),Inhibitory effect of magnetic Fe3O4 nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro; INTERNATIONAL JOURNAL OF NANOMEDICINE, 2016, 11: 4413~4422
(15) Guangying Sheng (#); Zhao Zeng(#) ; Jinlan Pan; Qinrong Wang; Hong Yao;Lijun Wen; Liang Ma; Depei Wu; Suning Chen (*)；t(1;9)(p34;q34)/SFPQ-ABL1 Fusion in a Patient with Ph-Like Common B-Cell Acute Lymphoblastic Leukemia, Acta Haematol, 2016.10.2, 137: 40~43
(16) Tongtong Zhang(#) ; Yang Xu (#); Jinlan Pan; Huiying Qiu; Depei Wu;Suning Chen(*); Aining Sun (*),Monosomal karyotype of chromosome 5/7 was an independent poor prognostic factor for Chinese myelodysplastic syndrome patients, Cancer Genetics, 2016.9, 209(9): 423~429
(17) Jiao Li(#) ; Lijun Wen; Junming Tang; Heng Zhang; Zhigang Zhou; Yunping Zhang; Yafeng Chen; Sisi Chen; Qiuxia Wang; Jianwei Shao; Wenzhong Wu; SuningChen (*),Prevalence of Monoclonal Gammopathy of Undetermined Significance in an Apparently Healthy Yixing Population in Mainland China, Acta Haematol, 2016.9.19, 137: 17~19
(18) Nana Wang(#) ; Xiaojin Wu(#) ; Guangying Sheng; Liang Ma; Lijun Wen; Hong Yao; Suning Chen (*)；MLL-SEPT5 Fusion Transcript in Two de novo Acute Myeloid Leukemia Patients With t(11;22)(q23;q11), General Laboratory Medicine, 2016.5.16, 36: 501~503
(19) Mengyun Li (#); Lijun Wen; Jiannong Cen; Yufeng Feng; Suning Chen(*)；JAK2V617F allele burden in patients with myeloproliferative neoplasms carrying Trisomy 9, and its relationship with clinical phenotypes, Int J Hematol, 2016.3.7, 103: 599~601
(20) Xu, Yang(#) ; Sun, Yanjun(#) ; Shen, Hongjie; Ding, Lin; Yang, Zhen; Qiu,Huiying; Sun, Aining; Chen, Suning (*); Wu, Depei (*)；Allogeneic hematopoietic stem cell transplantation could improve survival of cytogenetically normal adult acute myeloid leukemia patients with DNMT3A mutations;AMERICAN JOURNAL OF HEMATOLOGY, 2015.11, 90(11): 992~997
(21) Xiaolin Ma(#) ; Lijun Wen; Lili Wu; Qingrong Wang; Hong Yao; Qian Wang;Liang Ma; Suning Chen (*), C Rare occurrence of a STAT5B N642H mutation in adult T-cell acute lymphoblastic leukemia;ancer Genetics, 2015.1, 208(1–2):52~53
(22) Wenjuan Ma(#) ; Jian Liu(#) ; Jundan Xie (#); Xiuyan Zhang; Haixia Zhou;Hong Yao; Weiqi Zhan; Dawei Guo; Lingying Zhu; Lun Xiao; Depei Wu; Haiyan Xu;Suning Chen (*); Yun Zhao(*)；Modulating the Growth and Imatinib Sensitivity of Chronic Myeloid Leukemia Stem/Progenitor Cells with Pullulan/MicroRNA Nanoparticles In Vitro, Journal of Biomedical Nanotechnology, 2015.1.1, 11:1961~1974
(23) Shen, Hongjie(#) ; Chao, Hongying; Ding, Zixuan; Feng, Yufeng; Cen,Jiannong; Pan, Jinlan; He, Jun; Zhou, Ming; Chen, Zixing; Chen, Suning (*),CALR and ASXL1 mutation analysis in 190 patients with essential thrombocythemia.Leuk Lymphoma, 2015.5, 56(3): 820~822
(24) Wu L(#) ; Xu Y (#); Wang Q; Ruan C; Drexler HG; Wu D; Macleod RA;Chen s(*)；High frequency of cryptic chromosomal rearrangements involving the LMO2 gene in T-cell acute lymphoblastic;Haematologica, 2015.6, 100(6): E233~E236
(25) Lijun Wen(#) ; Jing Xia(#) ; Qinrong Wang; Hong Yao; Jundan Xie; Jinlan Pan; Yongquan Xue; Depei Wu; Suning Chen (*)；Prognostic impact of residual normal metaphases in acute myeloid leukemia with t(8;21)(q22;q22), Int J Hematol, 2015.8, 102(2): 205~210
(26) Wenxiu Cheng(#) ; Xiaofei Yan; Nana Ping; Suning Chen (*); Aining Sun(*)；A case of acute erythroleukemia with concurrence of BCR-ABL and FLT3-TKD（D835E）mutation, LEUKEMIA & LYMPHOMA , 2015.8, 56(8): 2463~2464
(27) Hong Yao(#) ; Jinlan Pan; Chunxiao Wu; Hongjie Shen; Jundan Xie; Qinrong Wang; Lijun Wen; Qian Wang; Liang Ma; Lili Wu; Yun Zhao; Aining Sun(*) ;Suning Chen (*),Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22), Molecular Cancer, 2015.4, 14
(28) Wenjuan Wang(#) ; Qian Wang; Tingting Tao; Aining Sun; Changgeng Ruan;Suning Chen(*) ,Identification of Two Novel b-Thalassemia Mutations (HBB:c.335-346del and HBB: c.108 C4G) in Han Chinese, Informa Healthcare, 2015.10,39(5): 359~61(44) Wang, Qinrong(#) ; Dong, Shasha(#) ; Yao, Hong; Wen, Lijun; Qiu, Huiying;Qin, Llili; Ma, Liang; Chen, Suning(*) , Rare Occurrence of the JAK1 Mutation in Acute Promyelocytic Leukemia Patients Haematologica, 2014.10.1, 99(10):E176~E178
(29) Jundan Xie(#) ; Qian Wang; Qinrong Wang; Hong Yao; Lijun Wen; Liang Ma;Depei Wu; Suning Chen (*),High frequency of BTG1 deletions in patients with BCR-ABL1–positive acute leukemia;Cancer Genetics, 2014.5, 207(5): 226~230
(30) Wang Xiuli(#); Dai Haiping (#) ; Wang Qian; Wang Qinrong; Xu Yang; Wang Ying; Su Aining; Ruan Jia; Chen Suning (*); Wu Depei(*) , EZH2 mutations are related to low blast percentage in bone marrow and -7/del(7q) in de novo acute myeloid leukemia. PLos One, 2013.4.21, 8(4)
(31) Yin, Jia(#) ; Xu, Yang(#) ; Pan, Jinlan; Wu, Chunxiao; Wang, Qinrong; Yao,Hong; Wen, Lijun; Tian, Xiaopeng; Wu, Depei; Sun, Aining (*)；Chen, Suning(*)；A BCR-JAK2 fusion gene from ins(22;9)(q11;p13p24) in a patient with atypical chronic myeloid leukemia , Acta Haematologica, 2013, 130(4): 251~253
(32) Cheng, Jijun (#); Guo, Shangqin(#)(*);Chen, Suning(#)；Mastriano, Stephen； J.; Liu, Chaochun; D'Alessio, Ana C.; Hysolli, Eriona; Guo, Yanwen; Yao,Hong; Megyola, Cynthia M.; Li, Dan; Liu, Jun; Pan, Wen; Roden, Christine A.;Zhou, Xiao-Ling; Heydari, Kartoosh; Chen, Jianjun; Park, In-Hyun; Ding, Ye;Zhang, Yi; Lu, Jun (*), An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis , Cell Reports, 2013.10,ell Reports, 2013.10, 5(2): 471~481
3、学术奖励
(1) 陈苏宁(3/10), 恶性血液肿瘤关键诊疗技术的创新和推广应用, 国务院, 科技进步, 国家二等奖, 2016.12.21
(2) 陈苏宁(3/11), 恶性血液肿瘤个体化治疗新策略的建立和推广, 江苏省人民政府,科技进步, 省部一等奖, 2016.2.19
(3) 陈苏宁(3/11), 恶性血液肿瘤诊疗关键技术的创新和推广, 教育部, 科技进步,省部一等奖, 2016.2.26
(4) 陈苏宁(2/10), 造血干细胞移植治疗恶性血液肿瘤关键技术的优化和推广, 中华医学会, 科技进步, 其他, 2015.12.21
(5) 陈苏宁(2/9), 造血干细胞移植治疗恶性血液肿瘤关键技术的优化和推广, 江苏省医学会, 科技进步, 其他, 2015.12.30
(6) 陈苏宁(3/9), 白血病中新的染色体异常、融合基因和白血病细胞系的研究, 江苏省人民政府, 科技进步, 省部一等奖, 2010.1.4
(7) 陈苏宁(1/1), 伴有t(6;11)(q27;q23)易位的裸小鼠高致瘤性人单核细胞白血病细胞系SHI-1的建立和鉴定, 全国优秀博士学位论文提名奖, 教育部, 自然科学, 2005

主持或参加科研项目（课题）及人才计划项目情况：
1.江苏省教育厅“江苏特聘教授”人才项目,江苏特聘教授,2017/月份-2019/月份,100万元,已结题, 主持
2. 利用基因编辑技术修正的造血干细胞治疗β-地中海贫血的临床研究 国家重点研发计划 2019.11-2024.12 388万元, 已结题, 主持
3. 骨髓增生异常综合征的规范化诊疗 江苏省科技支撑计划重点项目
2015.07-2018.06 200万元, 已结题, 主持
4. 江苏特聘教授 江苏省教育厅“江苏特聘教授”人才项目 2017.10-2020.10 100万元, 已结题, 主持
5. RUNX1基因突变在BCR-ABL1阳性白血病中的致病机制及靶向治疗研究 国自然面上项目 2020.01-2023.12 55万元, 已结题, 主持
6. 维甲酸分化综合征的发病机制及靶向治疗研究 国自然面上项目2022.01-2025.12 54万元, 在研, 主持
7.国家重点研发计划项目子课题,2016YFC0902803,白血病精准分子分型及个体化治疗临床体系建立,2016/07-2018/12,, 已结题, 主持
8.国家自然科学基金面上项目,81570139, NUP98重排白血病的致病机制研究,2016/01-2019/12, 55万元, , 已结题, 主持
9.国家自然科学基金面上项目,81070416,t(16;21)(p11;q22)/FUS-ERG融合基因相关急性白血病的生物学特征及发病机制研究,2011/01-2013/12,35万元,已结题,主持
10.国家863计划子项目,2013AA020202, 新一代高性能五分类血细胞分析系统研制, 2013/01-2015/12, 48万元, 已结题, 主持
11. 江苏省科技支撑计划重点项目,BE2015639, 骨髓增生异常综合征的规范化诊疗,2015/07-2018/06, 200万元, , 已结题, 主持
12.江苏省自然基金委杰出青年基金项目, BK2012006, PAX5新融合基因的克隆和致白血病机制研究,2012/07-2015/06, 100万元, 已结题, 主持
13.国家973计划子课题, 2011CB933501, 纳米材料在血细胞研究中的应用, 2011/01-2015/12, 100万元, 已结题, 主持
14.美国白血病淋巴瘤协会和国际华氏巨球蛋白血症基金会国际项目，Establishment and characterization of novel Waldenstr?m's Macroglobulinemia cell lines,2010/06-2013/05,20万美元,已结题,主持


获得学术奖励
2019-12-18 国家科学技术进步奖 中华人民共和国国务院 二等奖
2016-12-21 国家科学技术进步奖 中华人民共和国国务院 二等奖
2016-02-19 江苏省科学技术进步奖 江苏省人民政府 一等奖
2016-02-26 教育部科学技术进步奖 教育部 二等奖
2017-12-01 吴孟超医学青年基金奖 上海吴孟超医学基金会